Grants Awarded

The METAvivor Research Program was established in 2009 with the specific goal of funding stage IV metastatic breast cancer research to one day, end death from metastatic breast cancer (MBC). The following list includes current and past grant recipients along with their progress reports.

If you would like to go back to the main research page, click here

ACTIVE GRANT RECIPIENTS



2023

Swarnali Acharyya, PhD

Columbia University Irving Medical Center (CUIMC)

Presented by The Met Gala Santa Clarita in honor of Amy Steffe Lohmann and Eva Miranda Crawford

Targeting S100A9 signaling to treat therapy-resistant brain metastases in HER2+ breast cancer

Abstract Report

Jill Bargonetti, PhD

City University of New York at Hunter College

Presented in honor of Caroline McIntyre and in memory of Sandy Gagliardi, members of Living with MBC Support Group in DENJPA

Targeting Breast Cancer Metastasis by Combination Inhibition of CXCR4 and MDM2/MDM4

Abstract Report

Chen Changyan, PhD

Northeastern University, Boston

Presented by #LightUpMBC Ambassador Team In Memory of Jessica Moore

Repurposing Bryostatin-1 (a Protein Kinase C Inhibitor-Based Drug) for Treating Metastatic Breast Cancer

Abstract Report

Mathew Cherian, MD

The Ohio State University Comprehensive Cancer Center

Presented by the The Meadowbrook Country Club Rally For The Cure Fundraiser in memory of Elizabeth Stevens

Sulfatase 2 inhibition to intensify chemotherapy and immunotherapy responses in metastatic triple-negative breast cancer

Abstract Report

Monica Fornier, MD

Memorial Sloan Kettering Cancer Center

Presented in memory of Mrs. Holli Hoelscher Simon

A pilot study of the efficacy and safety of the sclerostin-inhibitor romosozumab as a bone-modifying agent for patients with metastatic breast cancer to bones, and osteoporosis or osteopenia with high risk of fracture

Abstract Report

Rinath Jeslesohn, MD

Dana Farber Cancer Institute

Presented by the Philadelphia METAvivor Gala in memory of Kerry O'Riordan McAdam and in honor of Jacqueline Beck

Integrative multi-omics and immune profiling with machine learning for optimization of treatment in metastatic hormone receptor positive breast cancer

Abstract Report

David Kamson, MD, PhD

Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins Hospital

Presented by Jacqueline Vranicar - In memory of Lindsay Block

A Translational Observational Biorepository and Management Study In Patients with Leptomeningeal Metastasis: The BIOLEPT Study

Abstract Report

Efi Kokkotou, MD, PhD, DSc

Beth Israel Deaconess Medical Center

Presented by the Minneapolis Metsquerade

Repurposing a Melanin-concentrating hormone (MCH) antagonist for the treatment of metastatic breast cancer

Abstract Report

Kathleen McEnnis, PhD

New Jersey Institute of Technology

Presented by #LightUpMBC Ambassadors in memory of Nola Addante and all lives lost too soon to MBC

Mesenchymal stem cells as platinum nanoparticle delivery system for metastatic breast cancer treatment

Abstract Report

Funda Meric-Bernstam, MD

The University of Texas MD Anderson Cancer Center

Presented By Jacquelyn Vranicar and Jacquelyn and Lindsay’s METAvivor Team in memory of Kelsey Granowski

Optimizing TROP2-targeted antibody-drug conjugate therapy in metastatic breast cancer

Abstract Report

Stefania Morganti, MD

Dana-Farber Cancer Institute

Presented by the Philadelphia METAvivor Gala in memory of Kerry O'Riordan McAdam and in honor of Jacqueline Beck

Tracking minimal residual disease via circulating tumor DNA in patients with HER2+ metastatic breast cancer and exceptional response to therapy

Abstract Report

Naiara Perurena, PhD, PharmD

Harvard Medical School and Brigham and Women's Hospital

Presented by the Minneapolis Metsquerade In Memory of Lindsay Block

Developing combinatorial therapeutic strategies for metastatic HER2+ breast cancer

Abstract Report

Angelina Regua, PhD

The University of Texas Health Science Center

Presented by Tonya’s Hope In Memory and Honor of Tonyia Lucas

Understanding and overcoming resistance of breast cancer brain metastases to RET inhibition,

Abstract Report

2022

Lin Zhang, PhD

The University of Texas MD Anderson Cancer Center

Presented in honor of Ashleigh Griffin

Altering the Metabolic Tumor Microenvironment to Impede Breast Cancer Brain Metastasis

Abstract Report

Min Yu, PhD

The University of Maryland School of Medicine, Baltimore

Presented in honor of Tara Kuipers - Creator of #LightUpMBC Color Fun Run

Targeting IGFBP3 signaling as a novel therapy for ESR1-Y537S mutant driven bone metastasis

Abstract Report

Theresa Vincent, PhD

New York University Grossman School of Medicine

Presented by The Met Gala Santa Clarita in honor of Eva Miranda Crawford and Amy Steffe Lohmann

Targeting breast cancer brain metastasis using a brain penetrable RNA Polymerase I inhibitor

Abstract Report

Ghada Sharif, PhD

Lombardi Comprehensive Cancer Center

Presented by Color Street Foundation

Targeting Occult Cancer Cell Subpopulations Driving Metastases Growth

Abstract Report

Summary Report

Andrew D. Seidman, MD

Memorial Sloan Kettering Cancer Center

Presented by Cycle4Helen in honor of Helen O'Leary

Untangling the role of the brain metastasis microenvironment in HER2 positive breast cancer brain metastases to inform rational systemic treatment strategies

Abstract Report

Summary Report

Axel Schönthal, PhD

University of Southern California

Presented in memory of Kerry O'Riordan McAdam and In Honor of Jacqueline Beck

Controlled Opening of the Blood-Brain Barrier to Enable Effective Therapeutic Access to Breast Cancer Brain Metastases

Abstract Report

Jitesh Pratap, PhD

Rush University

Presented by METAvivor's community of followers on social media in honor of all of those touched by metastatic breast cancer

Targeting microtubule dynamics and endosomal trafficking for bone metastasis of breast cancer

Abstract Report

Summary Report

Lluis Morey, PhD

Sylvester Comprehensive Cancer Center, University of Miami

Presented by The Pittsburgh Metsquerade in honor of members Amy Fletcher, Bindy Koontz, Roberta Thomas Szpara and Laura Williams

Dual targeting of an epigenetic machinery and a cellular receptor to block metastatic breast cancer

Abstract Report

Summary Report

Hui-Wen LO, PhD

McGovern Medical School at The University of Texas Health Science Center, Houston

Presented by METAvivor's community of followers on social media in honor of all of those touched by metastatic breast cancer

Targeting Breast Cancer Brain Metastases by an FDA-Approved Antifungal Drug and its Novel Analog

Abstract Report

Laurie Littlepage, PhD

University of Notre Dame

Targeting Endocrine Therapy Resistance in Bone Metastasis

Abstract Report

Jonathan Kessler, MD

City of Hope / Beckman Research Institute

Presented by Minneapolis Metsquerade in memory of Toniya Lucas and Rachael Masters

Combination of Immune Checkpoint Inhibitor and Hepatic Radioembolization for the Treatment of Liver-Dominant Metastatic Breast Cancer

Abstract Report

Summary Report

Ayesha Shajahan-Haq, PhD

Georgetown University

Presented by METAvivor's community of followers on social media in honor of all of those touched by metastatic breast cancer

Application of a novel ruthenium-based anticancer therapy in ER+ metastatic breast cancer

Abstract Report

Summary Report

Bisrat Debeb, DVM, PhD

The University of Texas MD Anderson Cancer Center

Targeting sEcad - PDI axis for the treatment of breast cancer brain metastasis

Abstract Report

Gokul Das, PhD

Roswell Park Comprehensive Cancer Center

Presented by METAvivor's community of followers on social media in honor of all of those touched by metastatic breast cancer

Repurposing Tamoxifen to Treat Molecularly Stratified Metastatic Triple Negative Breast Cancer

Abstract Report

Katherine Cook, PhD

Wake Forest University School of Medicine

Presented by Lake Norman Metsquerade in memory of Hilary Blake Hamilton

Improving ER+ bone metastatic breast cancer outcomes through metabolic re-programming of the microenvironment

Abstract Report

Elvin Blanco, PhD

Houston Methodist Research Institute

Presented by METAvivor's community of followers on social media in honor of all of those touched by metastatic breast cancer

Mitochondrial biogenesis for T-cell priming and enhanced immunotherapy in metastatic breast cancer

Abstract Report

Summary Report

Andrei Bakin, PhD

Roswell Park Comprehensive Cancer Center

Presented by #LightUpMBC Ambassador team in memory of Rosylin Weston

Development of Novel Immune Therapy Approaches for Metastatic Breast Cancer

Abstract Report

Summary Report

Prasanna Alluri, MD, PhD

The University of Texas Southwestern Medical Center at Dallas

Presented by #LightUpMBC Ambassador team in memory of Jessica Moore

Targeting CDK4/6 inhibitor resistance in patients with metastatic, ER-positive breast cancer

Abstract Report

Khalid Sossey-Alaoui, PhD

Case Western Reserve University and MetroHealth Medical Center

Role of YB1 in Triple Negative Breast Cancer Metastasis

Abstract Report

Summary Report

Danny Welch, PhD

University of Kansas Medical Center Research Institute

Presented by The Pittsburgh Metsquerade in honor of members: Jill Griffin, Andrea Dimond, Lori Czyzewski, and Sophia Holland

Mitochondrial Modifiers of Metastasis

Abstract Report

Summary Report

Stuart S. Martin, PhD

University of Maryland, Baltimore

Presented in memory of Kerry O'Riordan McAdam and in honor of Jacqueline Beck

Leveraging combined ctDNA and CTC analysis to optimize treatment for existing bone metastases

Abstract Report

Ines Velazquez-Quesada, PhD

Temple University, College of Engineering, Bioengineering Department

Presented in memory of Tonyia Lucas and her Hope To Find A Cure

Impact of the neuron - breast cancer cell interactions on the growth and survival of brain metastasis

Abstract Report

Quanyin HU, PhD

School of Pharmacy, University of Wisconsin-Madison

Presented In memory of Andi Myers and Elizabeth Seagraves Murray and those from the support group "Living with MBC in DENJPA" th

Targeted degradation of BET proteins in combination with immune checkpoint inhibitors for treating metastatic triple-negative breast cancer

Abstract Report

Summary Report

Ana Gomes, PhD

H. Lee Moffitt Cancer Center & Research Institute

Presented in memory of Molly B. Taylor

Metabolic vulnerabilities of dormant disseminated breast cancer cells

Abstract Report

Summary Report

Amanda Clark, PhD

University of Pittsburgh

Presented by Northwest Arkansas Metsquerade, Runway for Research

Extracellular vesicles regulate metastatic breast cancer dormancy in the liver

Abstract Report

Jennifer Caswell-Jin, MD

Stanford University School of Medicine

Presented by the Linda (LeClair) Sousa, A Better Dream Foundation in memory of Linda (LeClair) Sousa

Fibroblast growth factor receptor signaling and immune composition in estrogen receptor-positive metastatic breast cancer

Abstract Report

Summary Report

Corinne Beinat, PhD, BSc (Hons)

Stanford University School of Medicine

Presented in loving memory of Be Bold and Behold honorees Kathryn Petrides and Lisa M. Laudico

A Theranostic Strategy for Precision Imaging and Treatment of Metastatic Triple-Negative Breast cancer

Abstract Report

2021

Marjan Rafat, PhD

Vanderbilt University – Nashville, TN

Presented by the Bayhill 9 Holers and Friends, Honoring the Memory of Linda Pizzolato

An engineered bone marrow microenvironment model to investigate the impact of stiffness in breast cancer metastasis

Abstract Report

Carol Sartorius, PhD

University of Colorado, Denver, CO

Endocrine therapy driven reprogramming of circulating tumor cell-platelet interactions in driving late metastatic spread of ER+ breast cancer

Abstract Report

Summary Report

Kornelia Polyak, MD, PhD

Dana-Farber Cancer Institute, Boston, MA

Metastatic niche metabolomes and epigenetic heterogeneity in breast cancer

Abstract Report

Summary Report

Sara Tolaney, MD, MPH

Susan F. Smith Center for Women’s Cancers, Dana Farber Institute, Boston, MA

Presented by METAvivors of NJ in Memory of Donna Karlis

Enhancing the immunogenicity of PD-L1+ metastatic HR+ breast cancer via DNA damage

Abstract Report

Summary Report

Lisa Carey, MD

The University of North Carolina at Chapel Hill, Chapel Hill, NC

HARMONY: Harnessing the Analysis of RNA expression and Molecular subtype to Optimize Novel TherapY for metastatic breast cancer

Abstract Report

Nikhil Wagle, MD

Dana-Farber Cancer Institute

Presented by #LightUpMBC Ambassador team in memory of Jessica Moore

Convergent transcriptional states in resistant ER+ metastatic breast cancer

Abstract Report

Robert Schneider, PhD

New York University School of Medicine

Presented by Abbey Rapoport

Inhibition of Regulatory T cell (Treg) selective mRNA translation for the treatment of metastatic breast cancer metastasis

Abstract Report

Lalita Shevde-Samant, PhD

The University of Alabama at Birmingham

Presented in memory of Heather Holmes

Altering the metastatic immune niche to eradicate established breast cancer metastases

Abstract Report

Summary Report

Gangadhara Sareddy PhD

The University of Texas Health Science Center at San Antonio

Presented in memory of Erica Griffiths, Founder of Living with MBC DENJPA

Targeting TNBC brain metastases using a brain penetrable KDM1A inhibitor

Abstract Report

Davide Ruggero, PhD

University of California, San Francisco

Presented by METAvivor Fundraisers in honor of all people living with metastatic breast cancer

ERα is a novel RNA-binding protein controlling a post-transcriptional program underlying breast cancer metastasis

Abstract Report

Summary Report

Efi Kokkotou MD, PhD

Beth Israel Deaconess Medical Center

Presented by Minneapolis Metsquerade in memory of Kim Cesarek

Development of a functional predictor assay of therapeutic responses in Metastatic Breast Cancer

Abstract Report

Summary Report

Melanie Hayden Gephart MD, MAS

Stanford University

Presented by Be Bold and Behold in loving memory of honorees Jennie Byram and Erica Griffiths

Halting the Progression of Breast Cancer Brain Metastases By Targeting Tumor-Associated Microglia (TAMs)

Abstract Report

Jin Chen, PhD transferred to Julie Rhoades

Vanderbilt University Medical Center

Presented by METAvivor Facebook Fundraisers in honor of all people living with MBC

Targeting EphA2 receptor in breast-to-bone metastasis

Abstract Report

Summary Report

Changyan Chen, PhD

Northeastern University

Presented by METAvivor Facebook Fundraisers in honor of all people living with MBC

Targeting MGL for Developing Novel Strategy to Treat Refractory Breast Cancer

Abstract Report

Summary Report

Jennifer Wenzel, PhD, MS

Johns Hopkins University School of Nursing, School of Medicine (Oncology)

Presented by METAvivor Facebook Fundraisers in honor of all people living with MBC

Metastatic Treatment Decision Navigation: A Community Health Worker Model to Support Black Breast Cancer Patients and Decision Partners

Abstract Report

Summary Report

Dipali Sharma, MS, PhD

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Presented by Color Street Foundation

Racial Disparity in metastatic triple-negative breast cancer in African American women: Unraveling actionable molecular determinants

Abstract Report

Summary Report

Pranela Rameshwar, PhD

Rutgers University

Presented by METAvivor Facebook Fundraisers in honor of all people living with MBC

Towards precise treatment for metastatic breast cancer in black patients

Abstract Report

Summary Report

Isidore Rigoustos, PhD

Sidney Kimmel Medical College, Thomas Jefferson University

Presented by METAvivor Fundraisers in honor of all people living with MBC

Short RNAs Promote Metastases in an Ancestry-dependent Manner

Abstract Report

Melanie Hayden Gephart, MD, MAS

Stanford University

Presented by METAvivor Facebook Fundraisers in honor of all people living with MBC

Identification of Race-Specific Tumor-Immune Interactions in Breast-to-Brain Metastases of Black Women

Abstract Report

Rachel Freedman, MD, MPH

Dana-Farber Cancer Institute

Presented by #LightUpMBC Ambassador team in Memory of Gail Weisbrot

LIFT UP-Optimizing Care and Support for Women with Metastatic Breast Cancer Who Need it Most

Abstract Report

Summary Report

Yara Abdou, MD

The University of North Carolina at Chapel Hill

Presented in Memory of Chawnte’ Randall

Investigating Survivin as a novel target for immunotherapy in Black women with breast cancer

Abstract Report

Jill Bargonetti, PhD

City University of New York (CUNY) at Hunter College

Presented by NWA Metsquerade in Memory of Lisa Quinn and In Honor of Kelli Davis

Targeting Metastatic Breast Cancer Through the Mutant p53-PARP Axis

Abstract Report

Summary Report

Wen-Hsuan Yang, PhD

Cold Spring Harbor Laboratory

Presented by Philadelphia Metsquerade in honor of Jacquie Reynolds Beck and Kerry O’Riordan McAdam

Targeting metabolic symbiosis in the breast cancer brain metastasis tumor microenvironment

Abstract Report

Summary Report

Christina Wei, MD

City of Hope National Medical Center

Presented by K and J Road To a Cure in honor of Kerry O’Riordan McAdam and Jacquie Reynolds Beck

Hepatic natural killer cell dysregulation facilitates breast cancer liver metastasis

Abstract Report

Evanthia Roussos Torres, MD, PhD

University of Southern California, Keck School of Medicine, USC Norris Comprehensive Cancer Center

The Geaton & JoAnn DeCesaris Family Foundation Grant in memory of Kimberly Stafford

Bi-directional translation of differences in the immunosuppressive tumor microenvironment of primary versus metastatic HER2+ breast cancer

Abstract Report

Summary Report

Luis Solorio, PhD

Purdue University

Presented in honor of Susan Marr Williamson

Effect of Motion in the Metastatic Microenvironment

Abstract Report

Summary Report

Jawed Siddiqui, PhD

University of Nebraska Medical Center

Presented in memory of Heather Holmes

Therapeutic tareting of GFRAL/RET axis to overcome bone metastasis of breast cancer

Abstract Report

Amy Schade, PhD

Brigham & Women's Hospital

Presented in memory of Noel Shubert Weaver, who passed away of triple negative metastatic breast cancer

Developing effective combination therapies for metastatic TNBC by co-targeting epigenetic and oncogenic enzymes

Abstract Report

Jennifer Rosenbluth, MD, PhD

University of California San Francisco

Presented in memory of Catherine Hill

Developing therapeutic strategies for metastatic inflammatory breast cancer using patient-derived organoids

Abstract Report

Summary Report

Vadim Jucaud, PhD

Terasaki Institute for Biomedical Innovation

Presented by the Moore/Smith Family in memory of Carol Smith, wife, mother, friend and advocate

Microengineered approach to develop personalized monoclonal antibodies for metastatic breast cancer treatment

Abstract Report

Summary Report

Daniel Hollern, PhD, BS

The Salk Institute for Biological Studies

Presented by The Orlando Metsquerade in memory of Caitlin Kosma, wife, mother, friend and advocate

Using B cells to eliminate TNBC liver metastases

Abstract Report

Summary Report

2020

Adrian Lee, PhD

University of Pittsburgh, UPMC Hillman Cancer Center

Targeting RET for the treatment of breast cancer brain metastasis

Abstract Report

Summary Report

Blake “Eason” Hildreth, DVM, MS, PhD

University of Alabama, Birmingham

Targeting the CSF1R/PU.1 axis and PU.1/BET super-enhancer regulome in breast cancer bone metastasis

Abstract Report

Summary Report

Julie Di Martino, PhD

Icahn School of Medicine at Mount Sinai

Targeting dormant breast cancer cells with ACE inhibitors

Abstract Report

Nathan Reticker-Flynn, PhD

Stanford University

Targeting lymph node-induced immune tolerance to treat metastatic breast cancer

Abstract Report

Summary Report

Lou Song, PhD

University of Virginia

Oncogenic TRIM37 is a new driver of metastasis in triple negative breast cancer patients

Abstract Report

Tae-Hyung Kim, PhD

University of New Mexico

Harnessing cell mechanotype to regulate the immune evasion of highly metastatic breast cancer cells

Abstract Report

Summary Report

Reva Basho, MD

Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute

Presented by Metavivor Facebook Fundraisers

Tucatinib in Combination with Pembrolizumab and Trastuzumab for Patients with HER2+ Breast Cancer Brain Metastases

Abstract Report

Isaac Chan, MD, PhD

UT Southwestern Medical Center

Presented by #Lindasbug: A VW Beetle Fundraiser in Memory of Linda Kreizenbeck

Using natural killer cells to eliminate breast cancer metastases

Abstract Report

Jessica Christenson, PhD

University of Colorado Anschutz Medical Campus

Presented by Metavivor Facebook Fundraisers

Repurposing Lung Microenvironment Targeted Therapies for the Treatment of Established Breast Cancer Lung Metastases

Abstract Report

Erin Howe, PhD

University of Notre Dame-Harper Cancer Research Institute

Presented in memory of Erin Remme by Minneapolis Metsquerade

Targeting endosomal trafficking to enhance immune recognition of breast cancer brain metastases

Abstract Report

Natasha Hunter, MD

University of Washington

Presented by Metavivor Facebook Fundraisers

Tissue and liquid biopsy for breast cancer patients with bone-only metastases

Abstract Report

Dennis Jones, PhD

Boston University

Presented by Metavivor Facebook Fundraisers

Targeting breast cancer plasticity and immunosuppression in metastatic lymph nodes

Abstract Report

Summary Report

Srinivas Malladi, PhD

UT Southwestern Medical Center

Presented in Honor of Abbey Rapoport

Targeting vulnerabilities of immune-evasive HER2+ Breast Adenocarcinoma Metastasis Initiating Cells

Abstract Report

Summary Report

Diwakar Pattabiraman, PhD

Geisel School of Medicine at Dartmouth

Presented in memory of Dee Dee Miller by Play: CLE to Cure: MBC

Differentiation therapy for metastatic breast cancer

Abstract Report

Shreyas Rao, PhD

The University of Alabama

Presented by Metavivor Facebook Fundraisers

Engineered biomimetic hydrogels to probe metastatic tumor cell cluster–brain microenvironment interactions facilitating tumor progression

Abstract Report

Summary Report

Thu Truong, PhD

University of Minnesota, Masonic Cancer Center

Presented by MetaRaise DENJPA in Memory of Our Friend Patty Ann Baldwin

Progesterone receptor reprograms metabolic pathways to drive therapy resistant populations in metastatic breast cancer

Abstract Report

Summary Report

Yun Zhao, PhD

University of Notre Dame

Presented by Metavivor Facebook Fundraisers

Targeting the pitfall of chemo-immunotherapy: Immunosuppressive myeloid cells induced by apoptosis

Abstract Report

Guizhi Zhu, PhD

Virginia Commonwealth University

Presented by Southwest Florida Metsquerade in Memory of Amanda DeFiebre

Multi-epitope/di-adjuvant co-delivering albumin-binding vaccines (Medico-AlbiVax) for the combination immunotherapy of metastati

Abstract Report

Stacy Blain, PhD

The Research Foundation of the State of New York, SUNY Downstate Medical Center

Presented by #LightUpMBC and Moore Fight Moore Strong in memory of Jessica Moore

p27Kip1: A game changing target in metastatic breast cancer

Abstract Report

Summary Report

Fumito Ito, MD, PhD

Roswell Park Comprehensive Cancer Center Health Research Inc

Presented by Southwest Florida Metsquerade in Memory of Karin Petrocelli

In situ radio-immunotherapy to maximize the engagement of cross-presenting dendritic cells to treat metastatic breast cancer

Abstract Report

Summary Report

Bethany Kerr, PhD

Wake Forest School of Medicine

Presented in Honor of Beth Fairchild and Her Service to Metavivor Research and Support

Profiling combinatorial treatment response in early and late bone metastatic breast cancer

Abstract Report

Traci Lyons, PhD

University of Colorado Anschutz Medical Campus

Presented by Northwest Arkansas Metsquerade In Memory of Erin Leland

Targeting therapeutic vulnerabilities of endocrine therapy resistant ER+ metastatic breast cancer

Abstract Report

Summary Report

Steffi Oesterreich, PhD

University of Pittsburgh

Presented by Facebook Fundraisers

Targeting mesothelial – tumor cell interaction to treat invasive lobular cancer metastases

Abstract Report

Summary Report

Selvarangan Ponnazhagan, PhD

The University of Alabama at Birmingham

Presented by Metavivor Facebook Fundraisers

Co-targeting immunosuppression and skeletal pathology for metastatic breast cancer therapy

Abstract Report

Summary Report

Pranela Rameshwar, PhD

Rutgers New Jersey Medical School

Presented in honor of Tami Bowling and METAvivors of NJ

Preventing epigenetic-mediated DNA repair induced by bone marrow niche cells to eliminate drug resistance

Abstract Report

Summary Report

Brad St Croix, PhD

National Cancer Institute

Presented by Monica Hill’s Be Bold and Behold, In Loving Memory of Monica Hill and Jasmine Charles

Improving the therapeutic index of ADCs targeting metastatic breast cancer

Abstract Report

Summary Report

Alana Welm, PhD

University of Utah

Presented by 2020 New York Fashion Week in Memory of Halli Lannan

FORESEE: Functional precision oncology for metastatic breast cancer: a feasibility trial

Abstract Report

Summary Report

Danny Welch, PhD

University of Kansas Medical Center Research Institute, Inc.

Presented by #Cancerland in Memory of Champagne Joy

BMRS1 MSD: A potential new inhibitor of breast cancer metastasis

Abstract Report

Stuart Martin, PhD

University of Maryland School of Medicine

Presented by the We "Neeta" Cure Fundraiser in Memory of Neta Meier

Targeting Tau-induced microtubule stabilization to reduce outgrowth of metastatic tumors

Abstract Report

Summary Report

2019

Nancy Lin, MD

Dana-Farber Cancer Institute

Overcoming Treatment Resistance in Breast Cancer Brain Metastases

Abstract Report

Summary Report

Bolin Liu, PhD

Department of Genetics Stanley S. Scott Cancer Center School of Medicine Louisiana State University Health Sciences Center

Presented in Memory of Cecilia “CeCe” Curry, METAvivor Board Member

IGF-2 in Herceptin refractory HER2-positive breast cancer

Abstract Report

Summary Report

Paul Lockman, PhD

West Virginia University

Timing of radiotherapy and chemotherapy to improve drug effect in brain metastases of breast cancer

Abstract Report

Summary Report

Deepali Sachdev, BSc, MSc, PhD

Regents University

Presented by 2019 NYFW + #Cancerland in memory of Champagne Joy

Development of natural killer cell based tri-specific killer engagers (TriKEs) as novel immunotherapy for metastatic breast canc

Abstract Report

Summary Report

Robert Weinberg, PhD

Whitehead Institute for Biomedical Research

Mechanisms of Acquired Adaptation of Disseminated Breast Cancer Cells

Abstract Report

Summary Report

Fei Xing, PhD

Wake Forest University

Treating breast cancer brain metastasis with immune checkpoint inhibitor and c-Met targeting agent

Abstract Report

Summary Report

Massimo Cristofanilli, MD

Northwestern University

Presented In Memory of Karen Presswood, Co-Founder of METAvivor

Unravelling New Cytokine-Mediated Mechanisms to Enhance Response to CDK4/6 inhibition in ER+/HER2-Metastatic Breast Cancer

Abstract Report

Summary Report

Andrew Ewald, PhD

Johns Hopkins University, School of Medicine

Presented In Memory of Avis Halberstadt, Co-Founder of Metavivor

Targeting the survival pathways required by established breast cancer metastases

Abstract Report

Summary Report

Carol Lange, PhD

University of Minnesota

Presented In Memory of Rhonda Rhodes, Co-Founder of Metavivor

Targeting Activated Progesterone Receptors in Metastatic Breast Cancer

Abstract Report

Summary Report

Prasanna Alluri, MD, PhD

UT Southwestern Medical Center at Dallas

Presented in honor of Erin Remme by Minneapolis Metsquerade

Identifying Therapeutic Vulnerabilities in RB1-negative, ER-positive Breast Cancers

Abstract Report

Summary Report

Lucia Borriello, PhD

Albert Einstein College of Medicine

Presented by 2019 New York Fashion Week

Targeting the Mechanism of Re-Dissemination and Metastasis in Stage IV Breast Cancer

Abstract Report

Summary Report

Joshua Drago, MD

Memorial Sloan Kettering Cancer

Presented by METAvivors of New Jersey

The intestinal microbiome and response to chemoimmunotherapy in patients with metastatic triple negative breast cancer (MTNBC)

Abstract Report

Summary Report

Mick Edmonds, PhD, MS

UAB School of Medicine

Presented In Memory of Kristin Todd

A novel strategy targeting SRC tyrosine kinase for breast cancer metastasis

Abstract Report

Colt Egelston, PhD

City of Hope

Presented In Memory of Angie Powell by Northwest Arkansas Metsquerade

Bispecific monoclonal antibodies for treatment of advanced breast cancer

Abstract Report

Jeremy Force, DO, MA

Duke University

Presented In Memory of Kristie Godwin Rolan by Triangle Metsquerade

Discovery and validation of putative oncogenic ROS1 alterations in breast cancer

Abstract Report

Summary Report

Jamie Fornetti, BA, PhD

Huntsman Cancer Institute, University of Utah

Presented by Abbey Rapoport

Novel RON Inhibitors for the Treatment of Metastatic Breast Cancer

Abstract Report

Summary Report

Antonio Giordano, MD, PhD

Medical University of South Carolina

Presented In Honor of Michael Kovarik by 2019 New York Fashion Week

Phase 1 clinical trial of Polo-like kinase 1 inhibition with nab-paclitaxel in TP53 mutated metastatic triple negative breast ca

Abstract Report

Summary Report

Sheheryar Kabraji, BMBCh

Dana-Farber Cancer Institute

Presented by 2019 METAbash

Targeting drug-resistant quiescent cancer cells in breast cancer brain metastases

Abstract Report

Summary Report

Jungwoo Lee, PhD

University of Massachusetts Amherst

Tissue-engineered bone to determine the impact of chemotherapy-induced premature aging in breast tumor metastasis

Abstract Report

Summary Report

Michael Lukey, PhD

Cornell University

Presented by Minneapolis Metsquerade in honor of Erin Remme

Targeting the unique metabolic profile of brain metastases in breast cancer

Abstract Report

Summary Report

Ashley Makela, PhD

The Institute for Quantitative Health Science and Engineering, Michigan State University

Presented In Memory of Connie Cadwell by Miles4Metavivor

Understanding extracellular vesicle trafficking in established breast cancer metastases: In vivo tri-modal imaging provides long

Abstract Report

Summary Report

Madeline Oudin, BSc, MSc, PhD

Tufts University

Presented by METAribbon Challengers

Investigating how obesity-driven changes in the tumor microenvironment promote metastatic outgrowth and chemoresistance in metas

Abstract Report

Summary Report

Lijuan Sun, PhD

Cold Spring Harbor Laboratory

Presented In Memory of Rebecca McNally Gilden - Blessed mother, wife, daughter, engineer, friend and breast cancer advocate

Reprogramming innate-adaptive immune interactions to eliminate metastatic breast cancer

Abstract Report

Summary Report

Stuart Martin, PhD

University of Maryland School of Medicine

Presented In Memory of Wendy Taylor by Northwest Arkansas Metsquerade

Reducing the risk of chemotherapy-induced scattering of metastatic triple-negative breast tumors

Abstract Report

Danny Welch, PhD

University of Kansas Cancer Center

Presented In Memory of Valerie Wright by Northwest Arkansas Metsquerade

New inhibitors of breast cancer metastasis

Abstract Report

Andrei Bakin, PhD

Roswell Park Cancer Center

A Novel Combination Therapy to Improve Treatment of Metastatic Breast Cancer

Abstract Report

Summary Report

Sanchita Bhatnagar, PhD

University of Virginia School of Medicine

Targeting the mechanisms of oncogenic TRIM37 in metastatic triple negative breast cancer

Abstract Report

Summary Report

Rolf Brekken, PhD

UT Southwestern

Pleiotrophin as a driver of the immune metastatic niche

Abstract Report

Summary Report

Andrew Brenner, MD, PhD

Mays Cancer Center

Presented In Memory of Tarah Harvey by Minneapolis Metsquerade

Permeability of Sacituzumab Govitecan in Breast Cancer Brain Metastases

Abstract Report

Barbara Fingleton, PhD

Vanderbilt University

Presented In Memory of Destiny Rivera and Stephanie Sunday by Orlando Metsquerade

Tumor targeting of an immune super-activator in male and female metastatic breast cancer

Abstract Report

Barry Hudson, PhD

University of Miami

Presented in memory of Amanda De Fiebre by Southwest Florida Metsquerade

Therapeutic targeting of RAGE in metastatic breast cancer

Abstract Report

Summary Report

Yibin Kang, PhD

Princeton University

Presented by The Fraternal Order of Eagles

Preventing Regulatory T cell Induction to Enhance Immunity Against Breast Cancer Metastases

Abstract Report

Summary Report

Stephen Kron, MD, PhD

The University of Chicago

Mechanisms determining local and systemic anti-tumor immune response after metastasis-directed image-guided radiation combined w

Abstract Report

Summary Report

Sandra McAllister, PhD

Brigham and Women's Hospital; Harvard Medical School

Presented In Memory of Lauren Smoke by Chicago Metsquerade

A new approach to identifying effective therapeutic strategies that eliminate de novo and recurrent stage IV triple-negative bre

Abstract Report

Yusuke Shiozawa, MD, PhD

Wake Forest University

An osteolytic bone lesion-targeted radiopharmaceutical for bone metastatic breast cancer

Abstract Report

Summary Report

Zena Werb, PhD

University of California, San Francisco

Presented by METAvivor Facebook Fundraisers

Identification of Novel Cell Targets for Metastatic Breast Cancer Therapy

Abstract Report

Jing Yang, PhD

University of California, San Diego

Overcoming therapy resistance in TNBC metastases through targeted inhibition of Periostin

Abstract Report

Summary Report

Dihua Yu, PhD

The University of Texas

Presented In loving memory of Tiffany Foust and Kriss Fierro by Monica Hill's Be Bold and Behold

Impeding Breast Cancer Brain Metastasis by Blocking CCR2+ Myeloid Cell Infiltration

Abstract Report

Summary Report

View Past Grant Recipients